The Cannondale Synapse is a comfy ride with some of that Cannondale stiffness and snappy efficiency. The Synapse has received acclaim as a sportive bike, but only pure racers won't love this fantastic all-rounder. The Cannondale Synapse Tiagra and Cannondale Synapse 105 make up the approachable alloy frame Synapses. The Cannondale Synapse Carbon 105 starts the top-of-the-line carbon fiber version of one of the most popular bikes ever.